| 1967 | Hupac Ltd was established in Chiasso. The initial share capital was equal to 500,000 Swiss Franks; the first Chairman of the Board of Directors was Pietro Ris. |
| 1968 | Hupac started its activity with 10 wagons between Basle and Melide. Management was entrusted to Theo Allemann, the company’s historical manager for more than 30 years. |
| 1969 | Hupac carried out the first international combined transport with its own wagons on the Cologne/Milan Rogoredo stretch. |
| 1971 | Hupac entered into a service agreement with the German combined transport operator Kombiverkehr, for a better integration of the traffic in Northern Europe. |
| 1973 | The international activity of Hupac expanded considerably with the opening of the Milan/Rotterdam axis, which followed up an agreement with the Dutch company Trailstar. During the same year, the Italian branch of Hupac SpA was established; it assures the management of the terminal activity in Italy. |
| 1976 | Rolling Highway was added to unaccompanied traffic on the Altdorf/Cadenazzo stretch, which transports motor vehicles with drivers from one side to the other of the Alps. |
| 1978 | Transport activities started to be transferred to the Busto Arsizio terminal, which later became the main Hupac transfer centre in Italy. |
| 1980 | The Rolling Highway became international with a connection between Milano Greco Pirelli and Freiburg i. B. |
| 1981 | The cooperation between Cemat and Hupac led to a strong traffic development in Italy. |
| 1985 | Termi Ltd was established in Chiasso with the task of designing and building new intermodal terminals. |
| 1990 | The first shuttle train started running between Cologne and Busto Arsizio: an innovation destined to revolutionize the characteristics of the Hupac transport services. |
| 1992 | The new terminal of Busto Arsizio II was opened in the presence of minister Adolf Ogi. |
| 1995 | The whole Hupac Group attained the QMS certification according to ISO 9002 as a result of the introduction of more advanced procedures. |
| 1996 | Thanks to the innovative Shuttle system, Hupac was awarded the European Transport Prize. During the same year, the terminal of Singen was opened and Fidia, the management company of the Oleggio terminal, became part of the Hupac Group. |
| 1997 | Hupac's Environmental Management System also attained the ISO 14001 certification. |
| 1998 | Hupac took over the Dutch company Trailstar (later to become Hupac Intermodal NV) and expanded the connections on the Holland-Italy axis. |
| 1999 | Hupac opened in Basle the Maritime Inland Services branch to develop the maritime traffic. During the same year, Hupac acquired the railway licence in Germany. |
| 2001 | Hupac, SBB, BLS and Trenitalia established the RAlpin company for managing the Rolling Highway between Freiburg i. B. and Novara via Lötschberg/Simplon. During the same year, Hupac acquired the railway licence in Italy. |
| 2004 | Following an offer procedure, Hupac assigned the traction of its trains to five railway companies that assure integrated traction, i.e. a single haulage contractor from departure to arrival. |
| 2005 | The new terminal of Busto Arsizio-Gallarate was opened. It doubled the transfer capacity. Special guests were the ministers Moritz Leuenberger and Pietro Lunardi. |
| 2006 | The Hupac Intermodal BVBA was established in Antwerp, with the task of terminal engineering and management. |
| 2007 | First traffics via Brenner and in France. |
| 2008 | First traffics to Russia. |
| 2009 | First traffics to Romania. |
| 2010 | The terminals HTA Hupac Terminal Antwerp and Combinant (BASF, Hupac, IFB) start operations in Antwerp. The company’s own rolling stock workshop is opened at the Busto Arsizio-Gallarate terminal. During the same year, Hupac is certified as an ECM – Entity in Charge of Maintenance. |
| 2011 | Hupac Ltd took a share of 25% in SBB Cargo International AG. The Russian subsidiary Intermodal Express is opened in Moscow |
| 2012 | FSI, FS Logistica, Cemat and Hupac signed a Memorandum of Understanding for the development of terminal capacity in northern Italy. A wheel set reconditioning facility is opened in Busto Arsizio. During the same year, Hupac took over Centro Intermodale SpA, Milan, which manages the Piacenza terminal, |
